{"id":13445,"date":"2017-05-20T09:58:15","date_gmt":"2017-05-20T13:58:15","guid":{"rendered":"http:\/\/tvsef.ca\/?page_id=13445"},"modified":"2026-07-27T03:19:50","modified_gmt":"2026-07-27T07:19:50","slug":"matthew-zhou","status":"publish","type":"page","link":"https:\/\/tvsef.ca\/?page_id=13445","title":{"rendered":"Matthew Zhou"},"content":{"rendered":"\n
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\r\n \"Matthew\r\n<\/div>\r\n

Matthew ZhouNeuroprotective Effect of Indomethacin against Glutamate Induced ExcitotoxicityCentral S.S.<\/h3>\r\nNeuroinflammation plays a significant role in the progression of neurodegenerative diseases. This project studies the neuroprotective effect of indomethacin, a nonsteroidal anti-inflammatory drug, on rat cortical embryonic neurons exposed to an inflammatory environment caused by glutamate-induced excitotoxicity. Results show that indomethacin treatment does have a positive effect in reducing cell dying rates during glutamate excitotoxicity. This protective effect only exists when excessive glutamate is present.\r\n
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Award<\/th>\r\nValue<\/th>\r\n<\/tr>\r\n\r\n
Excellence Award - Intermediate\r\nGold Medal\r\nSponsor: Youth Science Canada<\/td>\r\n<\/td>\r\n<\/tr>\r\n
Western University Scholarship\r\nGold Medallist - $4000 Entrance Scholarship\r\nSponsor: Western University<\/td>\r\n$4000<\/td>\r\n<\/tr>\r\n\r\n\r\n<\/tbody>\r\n<\/table>\r\n

Biography<\/h3>\r\n I am a Grade 10 student at London Central Secondary School. My interests include music, mathematics, chess, and science. I started playing piano at the age of six and have won several awards at both regional and provincial competitions. Among these achievements include a Gold medal for the top Grade 10 RCM mark in Ontario. I also learned to play the violin at school. My interest in mathematics has led me to win multiple awards in math contests. I also enjoy playing chess and have won many awards in regional chess tournaments. This year, I was also on the school Junior Reach for the Top Team. My strong passion for neuroscience helped me develop my science fair project this year. After learning that neuroinflammation is a prominent feature in neurodegenerative diseases, I discovered that certain drugs called NSAIDS may be able to treat this inflammation. This inspired the creation of my project. With my strong interest in medical sciences, I hope to pursue a career in medicine. My advice for any newcomers to the science fair is to never ignore ideas that seem too difficult. With hard work and dedication, anything can be achieved!","_et_gb_content_width":"","footnotes":""},"class_list":["post-13445","page","type-page","status-publish","hentry"],"aioseo_notices":[],"aioseo_head":"\n\t\t\n\t\n\t\n\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t